LOGO SIMULATED MONOLITH™ POLYMERIC STATIONARY PHASES FOR LIQUID CHROMATOGRAPHY
  vanguardlc
     

STYROS™ SP  (Sulfopropyl)
High Capacity Strong Cation Exchangers.

Contents:

  • Product summary: 

STYROS™ SP is a high capacity Strong Cation Exchanger for High Throughput purification of proteins and peptides.
The base matrix that is fully pervious is made of highly crosslinked poly(styrene-divinylbenzene).
Our proprietary polymerization technique ensures that the beads are not brittle and as a result, free of leachables. 
The unique macroporous structure takes full advantage of the inner bead's surface area making it possible to run high speed, high resolution separation without any mass transfer restrictions.
STYROS™ SP provides high static and dynamic capacity for analytical and semi preparative separations.
It has an extremely high pressure tolerance, and can be used up to 5,000 psi.
High resolution separations can be achieved at high, as well as low flow rates.
The goal has been to provide seamless series of stationary phases that could facilitate the transition from analytical to semi preparative applications, all within the same products.
Our proprietary column packing are geared towards providing high batch to batch reproducibility. 

  • Key Features:

Feature 1:

Optimum protein capacity (measured with Lysozyme): 100 mg/ml 

Feature 2:

Although we have used pressures of up to 10,000 psi without irreversibly altering the structure of the beads, we recommend the following pressure limits:

4,000 psi for the XH series,

3,000 psi for the XP and XM series.

4,000 psi for the NB series 

4,000 psi for the MB series

Feature 3:

No measurable shrinking and/or swelling due to highly crosslinked nature of the beads.

  • Specifications:

Support Matrix Crosslinked Poly(styrene-divinylbenzene) 
Surface Functionalities
 STYROS™ SP
Sulfopropyl 
Shipping Solvent 30 % MeOH in DI Water
Packing Density 0.4 g/ml
Shrinkage/Swelling < 0.5 % under different salt or solvent concentrations
Maximum Pressure Tolerance 270 bar (4,000 psi,  27 MPa)

STYROS™ SP/XP
4.6  x 100 mm.
Standard separation of 4 proteins at  1,100 cm/hr
(3 ml/min).
Comparison With:
15 µm MONO-SIZED Cation Exchanger 
4.6  x 100 mm.
Same protein standards at lower salt gradient. 

Pressure drop comparison