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SIMULATED MONOLITH™ POLYMERIC STATIONARY PHASES FOR LIQUID CHROMATOGRAPHY | |
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STYROS™
Q and STYROS™ PA
are monolithic, fully uniform polymer based packing for anion
exchange chromatography of biomolecules such as proteins and
peptides, intended for use in high speed, high resolution
applications. The base matrix that is fully pervious is made of
highly crosslinked poly(styrene-divinylbenzene).
Our proprietary polymerization technique ensures that the beads are
not brittle and as a result, free of any leachables.
The unique macroporous structure takes full
advantage of the inner bead's surface area making it possible to run
high speed, high resolution separation without any mass transfer
restrictions.
STYROS™ Q and PA
provide an optimum static and dynamic capacity for analytical and
semi preparative separations.
They have extremely high pressure tolerance, and can be used up to
5,000 psi.
High resolution separation can be achieved at high, as well as low
flow rates.
The goal has been to provide seamless series of stationary phases
that could facilitate the transition from analytical to semi
preparative and preparative applications, all within the same
products.
Our proprietary column packing are geared towards providing high
batch to batch reproducibility.
Optimum protein capacity (measured with BSA)
40 mg/ml for STYROS™ Q and
40 mg/ml for STYROS™ PA
Although we have used pressures of up to 10,000 psi without irreversibly altering the structure of the beads, we recommend the following pressure limits:
4,000 psi for the XH series,
3,000 psi for the XP and XM series.
4,000 psi for the NB series
4,000 psi for the MB series
No measurable shrinking and/or swelling due to highly crosslinked nature of the beads.
| Support Matrix | Crosslinked Poly(styrene-divinylbenzene) |
| Surface Functionalities STYROS™ Q STYROS™ PA |
Quaternary Aminomethyl Polyamine |
| Shipping Solvent | 30 % MeOH in DI Water |
| Packing Density | 0.4 g/ml |
| Shrinkage/Swelling | < 0.5 % under different salt or solvent concentrations |
| Maximum Pressure Tolerance | 270 bar (4,000 psi, 27 MPa) |
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STYROS™
Q/NB 2.1 x 250 mm. |